Pharmacon™ Downflow Booths

Pharmacon™ Downflow Booths
  • Modular, easy-to-clean rigid design with minimal joints.
  • Single, Two-Stage or Three-Stage HEPA/ULPA filtration can be accommodated.
  • Removable bulkhead panels enable access to fine dust filter for service from inside the booth.
  • Re-circulatory Airflow or Single Pass Airflow if solvent or hazardous fumes are present in the process (may also require explosion proof electricals).
  • Cooling Coils can be fitted to offset heat gains in re-circulatory airflow systems.
  • HEPA/ULPA gel-seal downflow filters are replaceable from within the boot. Gel-seal is more reliable than conventional gasketed seals.
  • Voltage-compensating blower(s) ensure stable airflow.
  • Magnehelic gauges provide convenient and reliable means for monitoring booth airflow.
  • Booths ship knocked-down for site assembly.
  • Compact ceiling and rear plenums maximize usable work area while minimizing floor space.
  • IQ/OQ protocols available.
  • Energy-efficient tear-drop light fittings minimize airflow disruption.
  • Comprehensive factory and site acceptance tests include: filter integrity, particle count (air cleanliness), downflow velocity and uniformity, exhaust velocity/volume, containment zone verification, noise level, light intensity, temperature rise and electrical safety.
  • Containment performance verified according to the ISPE Good Practice Guide, Assessing the Particulate Containment Performance of Pharmaceutical Equipment.


  • Bag-in bag-out filter housings for safe filter change.
  • Total exhaust airflow.
  • Built-in cooling coils to offset booth temperature rise.
  • Facia cavities for computers, screens, printers.
  • Front PVC strips.
  • Services such as N2, water, compressed air.
  • Network connections.
  • Containment screen for high-containment applications.
  • Integral equipment such as drum lifters.
  • Hazardous area applications.
  • Temp and humidity control systems.
  • Entry and exit airlocks.
  • Touchscreen and digital pressure alarms in lieu of switches and pressure gauges.

Project Process Flow

  • Project Lead Received
  • Initial Contact by Esco Technical Sales Engineer On-Site Visit to Determine Customer Needs.
  • First Proposal Submitted Complete With Submittal Drawings and Quote.
  • Follow Up Visit(s) and Refinement(s) to Requirements.
  • Final Proposal Submitted, Agremeent on Commercial Details.
  • Customer Issues Purchase Order.
  • Mechanical and Electrical Engineering at Esco.
  • Customer Approval of Design and Drawings.
  • Fabrication and Assembly.
  • Integration of Externally Sourced Equipment (If Required).
  • Factory Acceptance Test at Esco with Documentation.
  • Packaging and Transport.
  • Field Service Installation and Site Acceptance Test.